EIF4E and head and neck squamous cell carcinoma: Data from TCGA showing the differential expression of eIF4E between the tumor and adjacent normal tissues are shown in Fig. 1B. Compared with adjacent normal tissues, eIF4E expression was significantly upregulated in BRCA, cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), head and neck squamous cell carcinoma (HNSC), liver hepatocellular carcinoma (LIHC), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), stomach adenocarcinoma (STAD), and uterine corpus endometrial carcinoma (UCEC).