EIF4E and lung carcinoma: However, in lung and gastric cancers, decreased expression of eIF4E was significantly associated with poor prognosis (lung cancer OS HR =0.86, 95% CI =0.76–0.98, P = 0.019; gastric cancer OS HR =0.54, 95% CI =0.44–0.65, P = 1.1e-10) (Fig. 3C-G).