Concerns regarding the changes of anaphylaxis-related hospitalisation codes, their impact on epidemiologic trends, and further incomplete identification of anaphylaxis cases have been described everywhere else [52], Our study will only ascertain hospitalisations or emergency department presentations where severe IgE-mediated hypersensitivity is implied (i.e. anaphylactic shock) or those labelled as anaphylactic reaction. Here, IGHE is linked to anaphylaxis.