For further clarification of the molecular mechanism of miR-23a-3p in GC, the modulation of miR-23a-3p on the PI3K/AKT pathway (PI3K, p-PI3K, AKT, p-AKT) was studied in MGC-803 cells (Figure 5), exposing the repression of the phosphorylation of PI3K and Akt via elevation of miR-23a-3p, while silencing of which manifested a promoted effect. The gene discussed is AKT1; the disease is gastric cancer.