MAPK3 and central nervous system cancer: Figure 8 shows that the AUC for AKT1, ALB, JUN, MAPK1, MAPK3, and TNF in glioma patients and normal controls was 0.898 (95% confidence interval (CI), 0.884–0.913; P < 0.05), 0.727 (95% CI, 0.703–0.750; P < 0.05), 0.764 (95% CI, 0.742–0.786; P < 0.05), 0.815 (95% CI, 0.795–0.835; P < 0.05), 0.562 (95% CI, 0.536–0.588; P > 0.05), and 0.929 (95% CI, 0.917–0.941; P < 0.05).