TSPOAP1 and amyotrophic lateral sclerosis: Furthermore, colocalization analyses identified two additional shared loci that were not genome-wide significant in the ALS GWAS: between ALS and PD at the GAK locus (rs34311866, PPH4 = 99%) and between ALS and AD at the TSPOAP1-AS1locus (rs2632516, PPH4 = 90%).