CD274 and pancreatic neoplasm: Similar to the results from the HY24409 model, in orthotopic pancreatic tumors formed by the HY24160 cell line, treatment with mifepristone also inhibited tumor growth (without affecting body weight) in a CTL-dependent manner (Supplementary Fig. 5a–e), promoted the infiltration and activity of cytotoxic T cells (Supplementary Fig. 5f–k), downregulated expression levels of PD-L1 and known GR-activated genes (Supplementary Fig. 5l–o), and upregulated MHC-I expression levels (Supplementary Fig. 5l–n).