Similarly, analysis of the gene expression data from The Cancer Genome Atlas (TCGA) revealed a positive correlation of NR3C1 mRNA levels with CD274 (encoding PD-L1) mRNA levels and a moderate inverse correlation of NR3C1 mRNA levels with HLA-A mRNA levels in pancreatic cancer (Fig. 8f, g). Here, HLA-A is linked to familial pancreatic carcinoma.