Notably, antibody-mediated depletion of CD8+ T cells (Supplementary Fig. 4c) abolished the tumor growth inhibition caused by GR knockdown (Fig. 3b–e) or mifepristone treatment (Fig. 3g–j), suggesting that CTLs mediate the observed anti-tumor effect of GR depletion or inhibition. The gene discussed is NR3C1; the disease is neoplasm.