Thus, to test whether MYH9-PRA may promote infection of other CoVs in human lung cells, we infected NC and PRA-A549 cells with two αCoVs (HCoV-229E and HCoV-NL63) and three βCoVs (SARS-CoV-1, MERS-CoV, and HCoV-HKU1). This evidence concerns the gene S100A6 and infection.