CircFGFR1 [21]and circZFR [22] sponge miR-381-3p or miR-101-3p to augment the progression and anti-PD-1 resistance in NSCLC, but hsa_circ_0008305 [23] and circ_0001649 [24]sponge miR-429/-200b-3p or miR-331-3p/-338-5p to depress TGF-β-induced EMT and metastasis in NSCLC. The gene discussed is TGFB1; the disease is non-small cell lung carcinoma.