We subsequently performed an overexpression assay of IL17A in PK15 cells, and then inoculated with GS2018 at a multiplicity of infection (MOI) of 1.0, which showed significant increase in IL17A (p < 0.01) at 24, 48 and 72 h after infection (Fig. 9b and Additional file 6: Fig. S1). The gene discussed is IL17A; the disease is infection.