ASF1B and melanoma: We further validated the function of ASF1B in melanoma, the OE-ASF1B groups exhibited obviously higher cell viability, while the Si-ASF1B groups presented significant lower cell viability than control cells (0.74 ± 0.07 in CON, 0.76 ± 0.03 in NC, 0.60 ± 0.04 in Si-ASF1B, 0.86 ± 0.05 in OE-ASF1B of A375 cells at 72 h; 0.74 ± 0.04 in CON, 0.76 ± 0.02 in NC, 0.58 ± 0.05 in Si-ASF1B, 0.88 ± 0.04 in OE-ASF1B of A875 cells at 72 h) (Figure 3(a)).