In our gene enrichment analysis of SNPs that were P<1x10-5 for association, our SNPs showed enrichment for only one biological pathway, the anti-citrullinated protein antibody positive rheumatoid arthritis (ACPA positive RA) pathway from the GWAS catalog, with a p-value of 9.36 × 10−6(FDR-adjusted p=1.70 × 10−2) as determined by GENE2FUNC. This evidence concerns the gene PRTN3 and rheumatoid arthritis.