The results of high-frequency keywords analysis show that the research of MCTs covers the aspects of the physiological roles of the different MCT isoforms, protein expression, glycolysis, poor prognosis, energy metabolism, apoptosis, tumor microenvironment (TME), energy metabolism reprogramming, and protein inhibitors, etc. Burst keywords from 2017 to 2020 were obtained as follows: tumor cell, breast cancer, apoptosis, cancer associated fibroblast (CAF), down regulation, cell proliferation, and AZD3659, which represent the development trend of MCTs. The gene discussed is SLC16A1; the disease is cancer.