In humans, high MCT1 and high MCT4 expression usually result in poor prognosis, whereas (aka SLC16A7) Isoform 2 in the MCT superfamily (MCT2) expression correlates with a favorable outcome.[37] Metabolic adaptation of cancer cells is necessary for their growth and survival, suggesting that MCTs represent a novel opportunity of cancer treatment and are promising targets for the prevention of cancer invasion and metastasis.[38–40]. Here, SLC16A3 is linked to cancer.