These conclusions were consistent with the physiological functions of CXCL3, that is, as a tumor-inducing factor, CXCL3 can promote the chemotaxis and angiogenesis process of a variety of cells, activate G-protein–coupled receptor, induce calcium mobilization and ERK phosphorylation, thus participate in tumor development [23–27]. The gene discussed is CXCL3; the disease is neoplasm.