Finally, accumulated evidence indicates that the unconventional secretion of cellular material is likely to underlie other neurological diseases, including Alzheimer's (i.e. tau protein; Zhang et al., 2021) and Parkinson's disease (i.e. alpha-synuclein; Nakamura et al., 2021), suggesting that protein secretion pathways are viable therapeutic targets for multiple forms of neurodegeneration. The gene discussed is YWHAQ; the disease is Parkinson disease.