NFKB1 and type 1 diabetes mellitus: Levels of ROS, MDA, TNF-α, IL-6, as well as the nuclear activity of NF-κB p65, were significantly increased but the nuclear activity of Nrf2 was significantly decreased in the liver of T1DM-induced rats as compared to control rats (Figures 3(A–D) and 4 (A–D)).