SREBF1 and type 1 diabetes mellitus: However, administration of CC to both the control + EA or T1DM + EA significantly increased mRNA levels SREBP1, SREBP2, FAS, HMGCoAR and decreased mRNA levels of PPARα, CPT1a, and CPT1b as compared to either the control + EA-treated rats or T1DM + EA-treated rats, respectively (Figure 6(A–C)).