PON1 and overnutrition: In Ireland, HDL CEC was negativelycorrelated with waist circumference and BMI in children at age 5 and9 years, suggesting that overnutrition may have a detrimental effecton HDL cholesterol efflux.23 Among childrenunder 6 years of age in India, decreased PON1 activity and antioxidantcapacity were observed in 30 malnourished children compared to 30healthy controls.24 Our results suggestthat improved maternal and child nutrition may improve HDL CEC amongchildren at 18 months of age.