Using a spontaneously hypertensive rats model, which simulates hypertension-induced left ventricular hypertrophy and metabolic syndrome, revealed that rats depict multiple variations in their CD36 sequence, this allowed identifying important aspects for the function of CD36 and its impact on the consumption of long-chain fatty acids in the heart, like that O-GlcNAcylation in the recruitment of CD36 to the membrane and N-glycosylation at asparagine 102 are crucial for the transport of long-chain fatty acids (Lauzier et al., 2011). This evidence concerns the gene CD36 and metabolic syndrome.