The transcriptional activities of integrin α1, α6, and β4 are positively modulated by the binding of oncogenic Myc to the consensus sequence sites (E box) in the promoter motif of certain integrins in CRC (Ni et al., 2005; Boudjadi and Beaulieu, 2016; Boudjadi et al., 2016; Beaulieu, 2019). This evidence concerns the gene MYC and colorectal carcinoma.