CDH1 and colorectal carcinoma: Slik et al. demonstrated that aberrant EMT-associated markers, including integrin β4, E-cadherin and zonula occludens-1 (ZO-1), could be detected by multiplex immunohistochemistry in tumor buds of stage II CRC, highlighting the potential role of integrins in EMT-like phenotypes of TB (Slik et al., 2019).