The expression of SMOC1 has been analyzed at the single-cell level of different types of tumors (Figure 5A), including CNS/brain tumors (GBM, glioma, aspartate aminotransferase, high-grade glioma, and oligodendroglioma), lung cancer (LUAD and nonsmall cell lung cancer), skin melanoma, renal cell carcinoma, chronic myelogenous leukemia, and BRCA. This evidence concerns the gene SMOC1 and cutaneous melanoma.