GPT and End Stage Liver Disease: After modifications, in the model for end-stage liver disease (MELD) era, Olthoff et al. created the most widely used definition of EAD, which was defined as meeting one or more of the following conditions: (1) bilirubin ≥10 mg/dL on post-operation day (POD) 7, (2) international normalized ratio (INR) ≥1.6 on POD 7, and (3) alanine aminotransferases (ALT) or aspartate aminotransferases (AST) >2,000 IU/L within the first 7 days (12).