Suppli et al. (29) had the most differentially expressed genes for HOC vs. NASH with 74 genes and Horvath et al. (31) had 15 genes, with eight genes overlapping between studies (SELENON, TNXRD3, PLG, MAOA, SAT2, ALOX5, GGT5, and ACSL4) (Figure 3). The gene discussed is ALOX5; the disease is metabolic dysfunction-associated steatohepatitis.