In colon cancer cells, the induction of DNA damage-inducible transcript 3 (DDIT3), which is associated with C-Jun N-terminal Kinase (JNK), mediates the process for ferrichrome to induce cell apoptosis, and notably, the ferrichrome is produced by Lactobacillus casei ATCC334 (27). This evidence concerns the gene DDIT3 and colonic neoplasm.