In colon cancer cells, the induction of DNA damage-inducible transcript 3 (DDIT3), which is associated with C-Jun N-terminal Kinase (JNK), mediates the process for ferrichrome to induce cell apoptosis, and notably, the ferrichrome is produced by Lactobacillus casei ATCC334 (27). The gene discussed is DDIT3; the disease is malignant colon neoplasm.