When Panaxadiol (PX) extracted from ginseng root was used to treat LPS-induced ALI, the results showed that PX effectively alleviated the pathological changes of ALI in mice, and PX inhibited ferroptosis had alleviated the symptoms of ALI by up-regulating keap1-Nrf2/HO-1 pathway (Li et al., 2021a). This evidence concerns the gene HMOX1 and acute respiratory distress syndrome.