As an oncogene during spindle formation or chromosome segregation (Bernal, et al., 2002; Li, et al., 2013), pituitary tumor-transforming gene-1 (PTTG1) is an independent poor prognostic factor in NSCLC patients (Wang, et al., 2016) and can elicit an immunogenic response in NSCLC patients (Chiriva-Internati, et al., 2014). This evidence concerns the gene PTTG1 and non-small cell lung carcinoma.