Liu et al. 's study confirmed that Selective recruitment of CXCR3 (+) B cells Bridges the pro-inflammatory interleukin-17 response and the polarization of tumorigenic macrophages in the tumor environment, and blocking the migration or function of CXCR3+ B cells may help to overcome HCC (Liu et al., 2015). The gene discussed is IL17A; the disease is hepatocellular carcinoma.