KCTD1 (potassium channel tetramerization domain containing 1) was reported to regulate the Wnt/β-catenin pathway (Li et al., 2014; Hu et al., 2020), and PCAT18 (prostate cancer-associated transcript 18, lncRNA), was found to promote the progression of colorectal or gastric cancer through miR-759 or miR-135b (Hu et al., 2020; Zhang et al., 2020), thus KCTD1_PCAT18 fusion may resulting in the development of cancer. The gene discussed is PCAT18; the disease is cancer.