CHKB and muscular dystrophy: She had a mildly elevated Creatine Kinase (CK) on serum from DOL1 (247, normal range 29–168 IU/L) such that a muscular dystrophy next generation sequencing (NGS) panel (sequencing of 33 genes and del/dup of 4; see Materials and Methods) was performed without significant findings (Mendell et al., 2012).