CPEB1 and metabolic dysfunction-associated steatohepatitis: CircRNA_002581 knockdown significantly attenuated lipid droplet accumulation and could sponge miR-122 to derepress its inhibition of target gene, cytoplasmic polyadenylation element-binding protein 1 (CPEB1), which might subsequently affect autophagy, thereby aggravating the progression of nonalcoholic steatohepatitis (NASH) (Jin et al., 2020).