Moreover, Woo et al. observed that the expression of miR-638, miR-4488, and miR-3591-3p in the PBMCs of BD patients, part of them suffered from ocular symptoms, was altered, which is associated with the production of IL-6, a pleiotropic cytokine implicated in the pathogenesis of many immune-mediated disorders including several types of non-infectious uveitis (Woo et al., 2016). This evidence concerns the gene IL6 and Behcet disease.