RAB7A and liver cancer: RAB7A can mediate the degradation of lipid droplets by the lipophagy pathway, increase the level of intracellular lipids, promote lipid peroxidation, and promote the ferroptosis of liver cancer cells induced by RSL3. Knockdown of the RAB7A gene inhibits lipophages and the degradation of lipid droplets, which can reverse RSL3-induced cell ferroptosis (Bai et al., 2019).