Hu et al. identified that pseudogene SUMOP13 depletion in HCC cells can restrain cell growth and lung metastasis by upregulated expression of E-cadherin, an epithelial marker, and downregulated the expression of the mesenchymal marker vimentin as well as MMP-2 and MMP-9 (Hu et al., 2021). This evidence concerns the gene MMP9 and hepatocellular carcinoma.