ZBTB32 and cholangiocarcinoma: Through cell transfection and cell phenotype assays, we observed a significant tumor suppressor role for ZBTB32 in CC cells: ZBTB32 upregulation caused a decrease in the cell proliferation (Ps < 0.001; Supplementary Figures S13C,D) and a significant decline in migratory (Ps < 0.001; Supplementary Figure S13E) and invasive (Ps < 0.001; Supplementary Figure S13F) abilities of HeLa and SiHa cells.