Most studies have reported that high expression levels of eIF4A significantly promote a cancer cell malignant phenotype (proliferation, invasion, migration, and EMT) and inhibit apoptosis (Modelska et al., 2015a; Li W. et al., 2017; Liang et al., 2017; Li et al., 2020b; Gao et al., 2020). This evidence concerns the gene EIF4A2 and cancer.