INS and cancer: KEGG pathway analyses indicated that ferroptosis-related DEGs were mainly enriched in the p53 signaling pathway, ferroptosis, kaposi sarcoma-associated herpesvirus infection, the IL-17 signaling pathway, microRNAs in cancer, the TNF signaling pathway, fluid shear stress and atherosclerosis, insulin resistance, the PI3K-Akt signaling pathway and the HIF-1 signaling pathway (Figure 2B).