TGFB1 and fibrosis: Our previous literature results illustrated that lncRNA 74.1 is poorly expressed in clinical tissue samples and in the TGF-β1-treated HK-2 cell fibrosis model, while treatment with lncRNA 74.1 can alleviate renal fibrosis through an autophagy-mediated oxidative stress defense mechanism (Xiao et al., 2019).