Similarly, rituximab (binding to CD20 of B cells) has the potential to be used for treatment of PR3-ANCA associated diseases (Yoshida et al., 2021) and PR3-ANCA-associated with granulomatosis with polyangiitis, rituximab was observed to maintain the remission with non-adverse effects (Eriksson, 2005). Here, PRTN3 is linked to granulomatosis with polyangiitis.