The IL-8 content in the medium of the ΔhtpG infection group was significantly lower than that of the WT infection group (p < 0.01) and tended to reduce (p = 0.09) when compared with the CΔhtpG infection group, while the CΔhtpG infection group displayed a reduction (p < 0.05) in IL-8 content relative to the WT infection group (p < 0.05). The gene discussed is CXCL8; the disease is infection.