Figure 6C (upper panel) shows that anti-IL-2 mAb could drop the CD4+CD25+ T cell population; this was especially impressive for the CD25+ high subpopulation 21 days after infection. The percentage of Foxp3+ cells inside gated CD4+CD25+ T cells has diminished by half of the numbers found in infected mice treated with rat IgG as a control within 21 days after infection (Figure 6C, lower panel). Here, CD4 is linked to infection.