The expression of GAD1 (r = -0.14, P = 9.2E-03) and SPP1 (r = -0.237, P = 8.32E-06) was negatively correlated, whereas EHHADH was positively correlated (r=-0.15, P =5.36E-03) with tumor purity (Figure 10A). Here, SPP1 is linked to neoplasm.