CBL and juvenile myelomonocytic leukemia: 5-year survival 56% males, 66% females (32); children with CBL-mutated JMML often experience spontaneous regression as well as a few patients with NRAS mutated JMML; the majority of patients requires allogeneic transplantation; allogeneic transplantation results in a disease-free survival of 52% (data from 2005) (62); survival at 10 years 0.39 for children after HSCT and 0.06 for children without HSCT (data from 1997) (37)