IL6 and lip and oral cavity carcinoma: The results showed that except for IL6, which was enriched in the iCAF population of xenograft tissues but myofibroblasts in the clinical samples, hallmark genes for myCAFs, iCAFs, and myofibroblasts were fairly consistent between the xenograft and clinical oral cancer tissues, suggesting a certain extent of conservation in non-immune stromal cell populations preserved in the current study (Figure 4C).