NETs could trap the human gastric cancer cell lines (i.e., MKN45, OCUM-1, NUGC-4) in vitro to promote their proliferation (130), facilitate a more aggressive mesenchymal phenotype of AGS cells (131), and strongly augment the metastasis of MKN45 cells on peritoneum, which could be inhibited by IP administration with DNase I (132); these findings suggest that NETs play an important role in peritoneal metastasis of gastric cancer. This evidence concerns the gene DNASE1 and gastric cancer.