In addition, C–X–C motif chemokine receptor 4 (CXCR4), C–X–C motif ligand 3 (CXCL3), and matrix metallopeptidase 7 (MMP7), also considered as positively correlated genes, were reported as oncogenic genes and facilitate growth, invasion, migration, and chemoresistance in gliomas (27–29). This evidence concerns the gene CXCR4 and central nervous system cancer.