analyzed upregulated genes in EGFRm NSCLC tumors and found that two of the top upregulated genes (NT5E and ADORA1) belonged to the CD73/adenosine pathway (89), suggesting that EGFRm NSCLC may leverage the CD73/adenosine axis to generate an immunosuppressive TME. Here, NT5E is linked to non-small cell lung carcinoma.