CGA and neoplasm: Patients with a change of CgA level greater than a 40% increase had a higher risk of tumor progression or recurrence than those with a change of CgA level less than a 40% increase (OR= 3.22, 95% CI: 1.11-9.34 in the univariate analysis; OR = 5.04, 95% CI: 1.31-19.4 in the multivariate analysis, adjusted for the age of diagnosis, grade, stage, functionality, and sex).