POLD1 expression was closely correlated with OS in several cancers, such as PRAD (HR=9.25; P=2.7e-04) and MESO (HR=2.71; P=1.7e-06), and DSS in KIRC (HR=1.93; P=7.4e-04) and ACC (HR=3.48; P=2.6e-06). Here, POLD1 is linked to cancer.