MICAL2 is widely expressed in various cancers, including glioblastoma (25), prostate cancer (26), bladder cancer (25), etc. MICAL2 participates in cell growth, cell apoptosis, axon guidance, and the transportation of vesicles by controlling the assembly and disassembly of actin (26, 27). The gene discussed is MICAL2; the disease is urinary bladder carcinoma.