Atypical chronic myelogenous leukemia (aCML), BCR/ABL1 negative is a rare disorder classified into the category of myelodysplastic/myeloproliferative neoplasms (MDS/MPN), according to the 2016 revision of the World Health organization (WHO) classification of myeloid neoplasms and acute leukemia (1). This evidence concerns the gene ABL1 and atypical chronic myeloid leukemia, BCR-ABL1 negative.