TNF and cancer: Furthermore, KEGG pathway analysis showed that differentially m6A methylated mRNAs were mostly involved in TNF signaling pathway and transcriptional misregulation in cancer (Figure 4G), differentially m6A methylated lncRNAs were mostly enriched in pathways in cancer and endocytosis (Figure 4H), and differentially m6A methylated circRNAs were mostly enriched in spliceosome and mRNA surveillance pathway (Figure 4I).