A recent study integrating PCR arrays, genome-wide microarray, and proteome analyses reaffirmed KRT19 and MSLN as OC-related proteins.25 Another OC study confirmed the overexpression of KRT19 and epithelial cell adhesion molecule (EPCAM) mRNA in circulating tumor cell-fraction samples, compared to peripheral blood samples.26 KRT19 is also known as CYFRA21-1 and has been extensively studied as a prognostic biomarker for OC that is complementary to CA125.27,28 Our PEA analysis yielded four KLKs (KLK6, 8, 10, 11) that had a considerable decrease in 67-78% of OC patients after surgery. The gene discussed is MSLN; the disease is neoplasm.