The high expression of SLC25A27 promoted the drug resistance of ccRCC cell lines to GSK429286A, AZD5582, CAP-232, TT-232, and TLN-232 but enhanced the drug sensitivity of ccRCC cell lines to amuvatinib, TANK_1366, and PLX-4720 (Figure 11(e)). The gene discussed is SLC25A27; the disease is nonpapillary renal cell carcinoma.